Re: Lifting twarzy - czy tylko chirurg?
Piotr, produkujemy enzym collagenase, ktory jest podstawa dla spejalnych lekow
stosowanych w kosmetologi pooperacyjnej i pourazowej, mozna tez zastosowac go
do kosmetologii korekcyjnej by uzunac siatke kolagenu, zmarszki i przebarwienia,
kuracja ok 90 dni bedzie kosztowac ok 2,500 USD. Lek dopuszczony przez Komisje
Ministerstwa Zdrowia Rosyjskiej Federacji.
Chesz wiecej wiedziec, napisz email@example.com
Dalej krotki opis po angielsku
In 1985 year Mrs. Olga Klimova, during analyze of different sea organisms which
live in Pacific Ocean near Kamchatka harbor, found in hepatopancrease of crab
Paralithodes Camtschatica the very small quantities of unique mixture of nine
proteases (36 kD, 35 (II) kD, 28 kD, 25 (I) kD, 25 (II) kD, 25 (III) kD which
all are similar to proteases from group of tripsines, and 32 kD, 35 (I) kD,
23kD which are analogues to proteases from new group of enzymes the first
founded in organism of langouste Astacus fluviatilis) with very selective
activity to destroy only not-live proteins but can hydrolyzed live collagen
even in big net or multi-layers structures. They have unique function of
division of collagen molecules not for two big parts only, but many small
parties – simple amino-acids useful for treated organism live cells as
construction material or energetic sources or easy eliminate by organism
without toxic effects. Activity of this Collagenases is not lower then 700
Since 1985 till 1997 the industrial technology of extraction and purification
of complex of nine proteases from hepatopancrease of crab Paralithodes
camtschatica was developed and necessary medical tests were provided.
Medicines are registered in Pharmacopoeia of The Russian Federation; RF patents
protect the technology.
Collagenases of microbial origin split triple spiral of native collagen in one
specific point (by peptide bond Gly-Leu or Gly-Ile) lying in distance near ¾ of
length of collagen molecule to N-end. At that initial intact collagenic fibrils
change into big soluble fragments (with intermolecular cross b-lacings).
Collagenases of microbial origin practically are not able hydrolyze peptides
generated during the native collagen degradation and split partially denatured
collagen (gelatin) very slow.
The enzymatic complex of collagenolytic proteases (collagenase) from
hydrobionts evinced collagenolytical as well as general proteolytic activity.
It means that influence of enzymatic complex is not limited to hydrolyze of
triple spiral of native structure of collagen only, but great fragments of
collagen remains to be in the solution the substrates for enzymatic complex of
collagenolytic proteases (collagenase) from hydrobionts and undergo subsequent
hydrolyze down to the individual amino acids. This process attended by
decreasing of original content of components of collagen with high molecular
mass and respective increasing of concentration of low-molecular components –
short peptides and individual amino acids. Besides, the enzymatic complex of
collagenolytic proteases (collagenase) from hydrobionts provides, comparing
with other collagenases, significantly deeper hydrolyze, which explained with
its capability to hydrolyze triple native structure of collagen as well as
partially denatured collagen.
NAME OF THE PREPARATION NORMATIVE DOCUMENTATION
Cosmetic polycollagenase certificate of conformance
POCC RU. ПK 06.BO5154
(together with Research Institute of Vishnevsky name) certificate of
POCC RU. ИМ09 B00395
Polycollagenase – K
drug Recommended and approved:
FGK Ministry of Healthcare RF No 29-251/5846
“Collagenolytic protease high purified”
“Collagenolytic protease for cosmetology” ТУ: 2639-003-ОП-03