Gość portalu: kasia napisał(a):
> A jest jakies wiarygodne zrodlo ( naukowe),bo podany link nie jest
> taki zrodlem,ze ta metoda dziala? Bo w szpitalu na Karowej tez
> wspominaja na zajeciach,ze ta metoda jest malo skuteczna,jezeli
> chodzi o antykoncepcje 'po'
proszę źródło: www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1883543
"Comparison of Yuzpe regimen, danazol, and mifepristone (RU486) in oral
A. M. Webb, J. Russell, and M. Elstein
Department of Obstetrics and Gynaecology, University of Manchester.
Small right arrow pointing to: This article has been cited by other articles in PMC.
OBJECTIVE--To compare the effectiveness and acceptability of three regimens of
postcoital contraception. DESIGN--Randomised group comparison of
ethinyloestradiol 100 micrograms plus levonorgestrel 500 micrograms repeated
after 12 hours (Yuzpe method); danazol 600 mg repeated after 12 hours; and
mifepristone 600 mg single dose. SETTING--Community family planning clinic.
SUBJECTS--616 consecutive women with regular cycles aged 16 to 45 years. MAIN
OUTCOME MEASURES--Number of pregnancies, incidence of side effects, and timing
of next period. RESULTS--The raw pregnancy rates (with 95% confidence intervals)
for the Yuzpe, danazol, and mifepristone groups were 2.62% (0.86% to 6.00%),
4.66% (2.15% to 8.67%), and 0% (0% to 1.87%) respectively. Overall, these rates
differed significantly (chi 2 = 8.988, df = 2; p = 0.011). The differences
between the mifepristone and Yuzpe groups and between the mifepristone and
danazol groups were also significant. Side effects were more common and more
severe in the Yuzpe group (133 women (70%)) than in either the danazol group (58
(30%)) or the mifepristone group (72 (37%)). The Yuzpe regimen tended to induce
bleeding early but mifepristone prolonged the cycle. Three women bled more than
seven days late in the Yuzpe group compared with 49 in the mifepristone group.
CONCLUSIONS--Mifepristone was effective in reducing expected pregnancy rates and
the Yuzpe method also had a clinical effect. Danazol had little or no effect. A
further multicentre trial is needed."
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