Re: amniopunkcja, zespół Downa..
Ale to nie są polskie dane
To są dane ze Stanów z monitoringu 35000 ciąż:
przeklejam Ci streszczenie:
OBJECTIVE: The purpose of this study was to quantify the contemporary
procedure-related loss rate after midtrimester amniocentesis using a database
generated from patients who were recruited to the First And Second Trimester
Evaluation of Risk for Aneuploidy trial. METHODS: A total of 35,003 unselected
patients from the general population with viable singleton pregnancies were
enrolled in the First And Second Trimester Evaluation of Risk for Aneuploidy
trial between 10 3/7 and 13 6/7 weeks gestation and followed up prospectively
for complete pregnancy outcome information. Patients who either did (study
group, n=3,096) or did not (control group, n=31,907) undergo midtrimester
amniocentesis were identified from the database. The rate of fetal loss less
than 24 weeks of gestation was compared between the two groups, and multiple
logistic regression analysis was used to adjust for potential confounders.
RESULTS: The spontaneous fetal loss rate less than 24 weeks of gestation in the
study group was 1.0% and was not statistically different from the background
0.94% rate seen in the control group (P=.74, 95% confidence interval -0.26%,
0.49%). The procedure-related loss rate after amniocentesis was 0.06% (1.0%
minus the background rate of 0.94%). Women undergoing amniocentesis were 1.1
times more likely to have a spontaneous loss (95% confidence interval 0.7-1.5).
CONCLUSION: The procedure-related fetal loss rate after midtrimester
amniocentesis performed on patients in a contemporary prospective clinical trial
was 0.06%. There was no significant difference in loss rates between those
undergoing amniocentesis and those not undergoing amniocentesis. LEVEL OF
i link do pubmedu
Loitering with content.