dradam121
25.12.09, 09:54
Pokazywac sie zaczely pierwsze materialy na temat tego, czy poddanie sie
szczepieniu przeciwko "swinskiej grypie" cokolwiek zmienia w przebiegu,
epidemiologicznym, schorzenia.
Takim tekstem jest opracowanie : Effectiveness of 2008-09 Trivalent Influenza
Vaccine against 2009 Pandemic Influenza A (H1N1)—United States, May-June 2009
P Gargiullo, PhD; D Shay, MD; J Katz, PhD; A Bramley, MPH; M Nowell, MPH; J
Michalove, MPH; L Kamimoto, MD; JA Singleton, MS; PJ Lu, PhD, MD; L Balluz,
ScD; A Siston, PhD Posted: 12/23/2009; Morbidity & Mortality Weekly Report.
2009;58(44):1241-1245. © 2009 Centers for Disease Control and Prevention (CDC)
Najbardziej interesujacym jest stwierdzenie : "These results, taken together
with other studies, do not support an effect of seasonal 2008-09 trivalent
influenza vaccine in either decreasing or increasing the risk for pandemic
influenza A (H1N1). The results are consistent with U.S. serologic and
immunologic data[3] and with findings from a recently published study from
Australia.[5] In the immunologic analyses, prevaccination and postvaccination
sera from recipients of seasonal influenza vaccines during 2005-2009 were
tested by microneutralization methods for levels of cross-reactive antibody to
2009 pandemic influenza A (H1N1) virus. After seasonal vaccination during the
2005-06, 2006-07, and 2008-09 influenza seasons, children aged < 10 years
lacked detectable neutralizing cross-reactive antibody to the 2009 pandemic
influenza A (H1N1) virus. Among adults aged > 18 years, vaccination with the
2007-08 or 2008-09 trivalent inactivated vaccine provided little or no
increase in cross-reactive antibody levels.[3]"
W szczegolnosci autorzy cytuja przypadki australijskie "In Australia,
investigators conducted a case-control study using data from sentinel
influenza surveillance practices to assess the effect of seasonal vaccine.[5]
In-house rRT-PCR assays were used to identify 212 patients with pandemic H1N1
influenza and 365 control patients who tested negative for influenza virus
infection. The investigators found no evidence that receipt of seasonal
influenza vaccine influenced the risk for being diagnosed with 2009 pandemic
influenza A (H1N1) virus infection in any age group (0-4, 5-19, 20-49, 50-64,
and > 65 years). The overall age-adjusted VE against pandemic virus illness
was 3% (CI = −56%-40%). "
Pozdrawiam zainteresowanych, zainteresowanych tematyka odsylam do materialu
zrodlowego. Ja osobiscie sie nie szczepie, podobnie zona.
