Dimenhydrinat-do Doki

Gość: Doki Re: Dimenhydrinat-do Doki IP: *.54-136-217.adsl.skynet.be 12.07.03, 19:31

Dimenhydrinate, czyli Aviomarin, jest, o ile pamietam, w
tabletkach po 50 mg. Oba te srodki sa podobne w
dzialaniu, bo naleza do tej samej grupy (laki
przeciwhistaminowe). Meclozine troche dluzej dziala od
dimenhydrinatu.

Znalazlem taki artykul:

Schmid R, Schick T, Steffen R, Tschopp A, Wilk T.
Comparison of Seven Commonly Used Agents for Prophylaxis
of Seasickness. J Travel Med. 1994 Dec 1;1(4):203-206.
ABSTRACT: The objective of the study was to compare the
efficacy and tolerability of seven drugs frequently used
for the prevention of seasickness: the drugs were namely
cinnarizine, cinnarizine with domperidone, cyclizine,
dimenhydrinate with caffeine, ginger root, meclozine with
caffeine, and scopolamine. The design was a randomized,
double-blind study with two arms. On ethical grounds, a
placebo group was not included as in a previous study, in
the same setting, 80% of the passengers not receiving
prophylactic drugs were seasick. The setting was in
Andenes (Norway) during a time period from July to
September 1992. Subjects were 1741 tourist volunteers who
were joining a whale safari. The main outcome measures
were vomiting, malaise (modified Graybiel criteria), and
subjective reports of adverse events. Follow up was
possible in 1489 volunteers (85.5%). In each active
treatment group, 4.1-10.2% experienced vomiting and
16.4-23.5% experienced malaise (not significant).
Equally, there was no significant difference in the
incidence and characteristics of adverse events reported
in the various medication groups. Scopolamine Transdermal
Therapeutic System (TTS) users exhibited slightly more
visual problems and the agent tended to be less
effective. Six of the seven medications may be
recommended for prevention of seasickness; scopolamine
TTS seems the least attractive.

Wniosek: wszystko jedno, co wezmiesz, sa one rownie
skuteczne. Plasterki ze skopolamina dostaly tu minusa za
pogorszenie ostrosci wzroku, ale te przynajmniej nie
usypiaja.

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aka10 Re: Dimenhydrinat-do Doki 12.07.03, 15:49

Glowny skladnik tej gumy do zucia jest powszechnie uzywany w tabletkach
przeciwko chorobie lokomocyjnej.Wtedy jednak zazwyczaj jest to 100 mg i jako
jedyne dzialanie uboczne podawana jest ospalosc.Chodzi mi o to,czy przy 20
mg,ktore jest w gumie do zucia,tez sie "zasypia na stojaco" i z drugiej
strony,to czy te 20 mg jest wystarczajace,zeby zadzialac.Pozdrawiam.
- Gość: Doki Re: Dimenhydrinat-do Doki IP: *.54-136-217.adsl.skynet.be 12.07.03, 19:31
  
  Dimenhydrinate, czyli Aviomarin, jest, o ile pamietam, w
  tabletkach po 50 mg. Oba te srodki sa podobne w
  dzialaniu, bo naleza do tej samej grupy (laki
  przeciwhistaminowe). Meclozine troche dluzej dziala od
  dimenhydrinatu.
  
  Znalazlem taki artykul:
  
  Schmid R, Schick T, Steffen R, Tschopp A, Wilk T.
  Comparison of Seven Commonly Used Agents for Prophylaxis
  of Seasickness. J Travel Med. 1994 Dec 1;1(4):203-206.
  ABSTRACT: The objective of the study was to compare the
  efficacy and tolerability of seven drugs frequently used
  for the prevention of seasickness: the drugs were namely
  cinnarizine, cinnarizine with domperidone, cyclizine,
  dimenhydrinate with caffeine, ginger root, meclozine with
  caffeine, and scopolamine. The design was a randomized,
  double-blind study with two arms. On ethical grounds, a
  placebo group was not included as in a previous study, in
  the same setting, 80% of the passengers not receiving
  prophylactic drugs were seasick. The setting was in
  Andenes (Norway) during a time period from July to
  September 1992. Subjects were 1741 tourist volunteers who
  were joining a whale safari. The main outcome measures
  were vomiting, malaise (modified Graybiel criteria), and
  subjective reports of adverse events. Follow up was
  possible in 1489 volunteers (85.5%). In each active
  treatment group, 4.1-10.2% experienced vomiting and
  16.4-23.5% experienced malaise (not significant).
  Equally, there was no significant difference in the
  incidence and characteristics of adverse events reported
  in the various medication groups. Scopolamine Transdermal
  Therapeutic System (TTS) users exhibited slightly more
  visual problems and the agent tended to be less
  effective. Six of the seven medications may be
  recommended for prevention of seasickness; scopolamine
  TTS seems the least attractive.
  
  Wniosek: wszystko jedno, co wezmiesz, sa one rownie
  skuteczne. Plasterki ze skopolamina dostaly tu minusa za
  pogorszenie ostrosci wzroku, ale te przynajmniej nie
  usypiaja.
  - aka10 Re: Dimenhydrinat-do Doki 12.07.03, 21:37
    
    Dzieki za odpowiedz.Aviomarinu juz bardzo dawno nie uzywalam.Tu,gdzie mieszkam
    bez recepty dostepny jest tylko srodek z "meclozini hydrochloridum",25 mg.
    Wszystko inne,tzn.leki z "cyclizin"(50 mg),"promethazin"(25
    mg),"dimenhydrinat"(100 mg),"cinarizin" i "scopolamin"(1 mg/72 godz) sa na
    recepte.Plastrow nie przepisuje sie dzieciom ponizej 10 roku zycia i osobom
    powyzej 65 roku zycia,ze wzgledu na dzialania uboczne.Pozdrawiam.

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