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PODSTAWOWA WIEDZA

26.06.14, 18:12
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    • bbeap Re: PODSTAWOWA WIEDZA 26.06.14, 18:23
      Jak wazne sa tez probiotyki
      www.personalconsult.com/posts/2012-lyme-disease-pearls.html
      www.personalconsult.com/articles/letters-from-doctors-about-theralac.html
      • bbeap Re: PODSTAWOWA WIEDZA 26.06.14, 19:20
        Inna bardzo wazna a ignorowana rzecz - toksyny

        The use of CSM for binding mold biotoxins was clearly established many years ago in sample articles such as:
        In vitro and in vivo studies to assess the effectiveness of cholestyramine as a binding agent for fumonisins.
        Solfrizzo M, Visconti A, Avantaggiato G, Torres A, Chulze S.
        Istituto Tossine e Micotossine da Parassiti Vegetali, CNR, Bari, Italy. itmpms12@area.area.ba.cnr.it
        Several adsorbent materials were tested at I mg/ml for their in vitro capacity to adsorb fumonisin B1(FB1) from aqueous solutions. Cholestyramine showed the best adsorption capacity (85% from a solution containing 200 microg/ml FB1) followed by activated carbon (62% FB1). Bentonite adsorbed only 12% of the toxin from a solution containing 13 microg/ml FB1, while celite was not effective even at the lowest tested FB1 concentration (3.2 microg/ml). Cholestyramine was tested in vivo to evaluate its capacity to reduce the bioavailability of fumonisins (FBs) in rats fed diet contaminated with toxigenic Fusarium verticillioides culture material. Rats were exposed for one week to FBs-free diet, FBs-contaminated diet containing 6 or 20 microg/g FB1 + FB2 and the same FBs-contaminated diet added of 20 mg/g cholestyramine. The increase of sphinganine/sphingosine (SA/SO) ratio in urine and kidney of treated rats was used as specific and sensitive biomarker of fumonisin exposure. The addition of cholestyramine to the FBs-contaminated diets consistently reduced the effect of FBs by reducing significantly (P < 0.05) both urinary and renal SA/SO ratios.
        Mycopathologia. 2001;151(3):147-53.
        *****
        Cholestyramine protection against ochratoxin A toxicity: role of ochratoxin A sorption by the resin and bile acid enterohepatic circulation.
        Kerkadi A, Barriault C, Marquardt RR, Frohlich AA, Yousef IM, Zhu XX, Tuchweber B.
        Department of Nutrition, Universite de Montreal, Quebec, Canada.
        We have shown that the addition of cholestyramine (CHA, a resin known to bind bile salts in the gastrointestinal tract) to ochratoxin A (OTA)-contaminated rat diets reduced plasma levels of the toxin and prevented OTA-induced nephrotoxicity. To elucidate the mechanism of action of CHA, we carried out in vitro experiments to determine whether the resin may bind the toxin. For comparative purposes, binding of bile salts to the resin was also examined. Results showed that CHA binds both OTA and bile salts (taurodeoxycholate [TDC] and taurocholate [TCA]). Also, CHA showed greater affinity for OTA and TDC than for TCA. At 1 mM concentration, 96% of OTA and 80% of TDC were bound to the resin, while for TCA binding was only 50%. However, saturation of the resin was reached at higher levels with bile acids compared to OTA (3.67 mmol/g resin for TCA and 3.71 mmol/g resin for TDC versus 2.85 mmol/g resin for OTA). To characterize the nature of the binding of the toxin to CHA, NaCl (0 to 200 mM) was added to a fixed amount of OTA or bile acids. As expected, TCA absorption was decreased by the addition of NaCl (<50 mM), indicating electrostatic binding. However, OTA and TDC sorption was decreased only at high concentrations of NaCl (>150 mM), suggesting a stronger binding to the resin than that shown with TCA. Sequential competitive studies demonstrated that CHA binds more OTA than TCA. Yny articles exist as early as the 70's with cholestyramine binding a very wide range of biotoxins. For example:
        Partial purificaion of a toxin found in hamsters with antibiotic-associated colitis and reversible binding of the toxin by cholestyramine.
        Humphrey CD, Condon CW, Cantey JR, Pittman FE.
        Gastroenterology. 1979 Mar;76(3):468-76.
        ****
        The ability of cholestyramine resin and other adsorbents to bind Escherichia coli enterotoxins.
        Mullan NA, Burgess MN, Bywater RJ, Newsome PM.
        Several adsorbent materials were evaluated for their ability to bind Escherichia coli enterotoxins. Cholestyramine, a strong anion-exchange resin, bound the heat-labile and the heat-stable types of enterotoxin and reduced significantly their effects ...
        J Med Microbiol. 1979 Nov;12(4):487-96.

        www.personalconsult.com/articles/lymeendotoxins.html
        www.personalconsult.com/articles/morelymebiotoxinevidence.html
        www.personalconsult.com/articles/cholestyramineformold.html
        • bbeap Re: PODSTAWOWA WIEDZA 27.06.14, 14:30
          www.personalconsult.com/posts/treatment-of-protomyxzoa-rheumatica.html
          www.mdjunction.com/forums/lyme-disease-support-forums/general-support/10050072-fl1953-protomyxzoa-rheumatica
          Ksiazka pt Combating Biofilms
          www.lymebook.com/combating-biofilms-james-schaller
          Biofilmy to norma w chronicznej chorobie z lyme...
          • miroslaw111 Re: PODSTAWOWA WIEDZA 27.06.14, 15:38
            kawał dobrych materiałów
            ę
            niestety borelioza w fazie chronicznej lub z licznymi koinfekcjami to bardzo trduno leczące ustrojstwo więc niestety trzeba koniecznie sobie to przetłumaczyć, zwykły zakażnik nas z tego nie wyciągnie, ILADS też nie daje pewności
          • bbeap Re: PODSTAWOWA WIEDZA 27.06.14, 16:22
            Toksyny
            Metale ciezkie i/lub plesn/wilgoc tj mycotoxins
            www.personalconsult.com/articles/wellwaterheavymetal.html
            www.personalconsult.com/articles/moldandbiotoxins/toxicmoldkillercells.html
            • bbeap Re: PODSTAWOWA WIEDZA 27.06.14, 19:40
              Hormony
              www.personalconsult.com/articles/naturalhormonereplacement.html
              www.personalconsult.com/articles/maximizingemotions.html
              www.personalconsult.com/articles/youtakehormones.html
              • bbeap Re: PODSTAWOWA WIEDZA 27.06.14, 19:41
                Inflamacja i autoimmunologia
                www.personalconsult.com/articles/vipinflammation.html
    • bbeap Re: PODSTAWOWA WIEDZA 28.06.14, 13:01
      www.personalconsult.com/posts/checklists-for-babesia-bartonella-and-lyme-disease.html
      • bbeap Re: PODSTAWOWA WIEDZA 28.06.14, 14:25
        www.personalconsult.com/posts/artemisinin-poor-treatment.html
    • gucio070 Re: PODSTAWOWA WIEDZA 30.06.14, 23:19
      bbeap, czy możesz do mnie napisać na adres gucio070@gmail.com. Z góry bardzo dziękuję.
      • bbeap Re: PODSTAWOWA WIEDZA 23.07.14, 19:43
        Napisalam.
        • bbeap Re: PODSTAWOWA WIEDZA 04.09.14, 16:57
          www.townsendletter.com/July2014/mold0714.html

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