Klindamycyna

[tosho]

Już kiedyś było o tym na forum, ale wklejam raz jeszcze.
Jest to o klindamycynie - formie dożylnej i doustnej.
(praktyka dr-a Jemseka jemsekspecialty.com/files/DetailedLymeOverview.pdf )



The use of IV clindamycin has now become routine in our treatment protocol for
advanced neuroborreliosis. This change came about after we began using oral
clindamycin (with mepron) empirically for suspected cases of babesiosis
coinfection in our most recalcitrant, unresponsive patients. We immediately
noted some new and positive developments, e.g. absence of fever and night
sweats for the first time in months/years, increased mental acuity, and so
forth. Other patients had Herxheimer reactions that they had not experienced
for weeks on prior therapy, even though we were treating aggressively with
both intravenous and oral antibiotics.

Since our most debilitated patients were already on IV therapy, we decided to
try short courses of IV clindamycin and the effect has been consistently
impressive, even more so than with the oral formulation. We have now gone back
and retreated those patients who have had an incomplete response to prolonged
IV therapy, and in 11/12 of these cases, improvement on IV Clindamycin has
been dramatic. We are currently in the process of evaluating the optimal use
of clindamycin, as we continually do with all of the therapies we employ. Our
hope is that these more intensive therapeutic programs still provided in such
a way that they are tolerated, will allow us to shorten the IV program by
hastening the time to clinical improvement.

[tosho]

It is interesting to speculate that metronidazole (flagyl), which is arguably
the most potent anaerobic antimicrobial available, and which is used by LD
treating physicians to eradicate the cystic form of Bb (see below), may actually
be effectively treating some highly anaerobic Bb strains which ceftriaxone and
other commonly used antimicrobials would not be expected to eradicate (see
below) The venerable antibiotic clindamycin, which has excellent activity
against both strict anaerobes and facultative anaerobes, may provide a
therapeutic option not generally employed by others and certainly not recognized
to date in the Lyme literature. At the Jemsek Specialty Clinic, we have treated
over 30 patients to date with either oral or IV clindamycin as adjunctive
therapy to their main program (see treatment section below). In our more
difficult cases where response to intensive combination antimicrobials was not
forthcoming, we serendipitously discovered positive clinical responses whenever
clindamycin was employed in therapy. Since then, we have been consistently and
profoundly impressed by the clinical response to clindamycin therapy,
particularly when administered intravenously. Thus, in our view, clindamycin may
ascend to a role of first line intravenous therapy, alone or in combination with
more conventional approaches such as ceftriaxone or imipenem.

[tosho]

Co ciekawe klindamycyna działa też na mykoplazmy.

[nataszkam]

To pewnie i na CPN...

[tosho]

Od specjalisty ze strony www.cpnhelp.org dostałem info , że akurat na
chlamydie jest kiepska klindamycyna.

[franiolek1]

Widzialam klindamycyne w leczeniu babesji....
Probujesz Tosho? U nas to sie chyba nazywa Dalacin, i nie znam
nikogo, kto by to u nas bral.

[tosho]

'Dalacin C' lub 'Klimicin'

Franiolek - na razie dr Beata kazała kontynuować to co teraz biorę i tego się
trzymam.
Ale może kiedyś...

[mariano_84]

Brałem kiedyś ten antybiotyk po dłutowaniu 8. Było to w lutym 2006r i sporo rzeczy zaczęło sie poprawiać. Po południu czułem sie jakoś dziwnie. W sumie brałem to jakiś tydzień czasu - bez rewelacji.

[lymeric]

witam wszytskich,
ja bralam kiedys klindamycyne, okolo 3 tygodni. Przez pierwsze 3 dni
dozylnie, a potem w tabletkach. Lezalam wtedy w szpitalu w Szkocji.
Na tylnej czesci nogi pojawilo mi sie czerwona okragla
opuchnieta "plama", goraczkowalam, nie mialm apetytu, czulam sie
jakbym umierala. Po jednym dniu klindamycyny znacznie sie poprawilo,
po 3 dniach to co mialam na nodze praktycznie zniknelo.
W szpitalu za bardzo nie wiedzili co to jest i skad moge to miec - w
wypisie napisali: "leg cellulitis" czyli cos w stylu zapalenie
tkanki łacznej.
oczywiscie tak jak wy nazleze do borelczykow. Wciaż bujam się z
moimi objawami. Trzykrotnie robilam test Borelioza Total, mam
wskaznik okolo 1,5 (pow. 1 pozytywny). Myslę, że kleszcz dopadl mnie
okolo 10 lat temu. Klindamycyne bralam w 2006 roku. Mi pomogla w
tamtej sytuacji. Ale gdzies czytalam, ze przy dluszym stosowaniu
szkodzi.