Clenbuterol

[Gość: john]

"However, clenbuterol also yielded three very negative changes. First, after
just four weeks, clenbuterol-treated rats were unable to maintain their normal
swimming or running training intensities, while clean rodents were quite
capable of continuing. Secondly, the hearts of the clenbuterol-taking, trained
rats increased dramatically in size compared to the hearts of sedentary rats,
but the heart expansion was probably due to the infiltration of collagen
fibres into the heart walls, not an increase in heart-muscle cells. Collagen
is a tough connective tissue which doesn't augment heart-muscle power but in
fact stiffens the heart, potentially leading to a decrease in cardiac output.
Increases in collagen may also produce cardiac arrhythmias. Thirdly,
clenbuterol rats suffered from noticeable cardiac-cell degeneration."

The Effects of Clenbuterol on Skeletal and Cardiac Muscle of Rats when
Combined with Aerobic and Anaerobic Exercise, ' Biochemistry of Exercise Ninth
International Conference Abstracts, #117, p 75, 1994